CASE STUDY: 19-Year-Old Woman Believes COVID Jab Caused Massive Bre*st Growth, Dubbed ‘Pfizer B**b Job’

A team of researchers from the University of Toronto documented a case study of a 19-year-old woman whose breast size massively enlarged after receiving the COVID-19 jab.

The woman’s breasts grew from a B cup to a triple G in six months post-inoculation.

“True parenchymal breast changes following COVID-19 vaccination are exceedingly rare. Equally rare are incidences of pseudoangiomatous stromal hyperplasia (PASH)–associated gigantomastia. The patient in this case report presented with both occurrences and experienced massive breast enlargement 1 week postadministration of the Pfizer/BioNTech COVID-19 vaccine, which worsened after her second dose,” the researchers wrote in the Plastic & Reconstructive Surgery-Global Open journal.

“Definitive treatment was achieved through reduction mammoplasty, with the final pathology report confirming uniformly dense terminal duct lobular units with interspersed PASH units. The association between the COVID-19 vaccine, PASH, and breast hypertrophy warrants further investigation to comprehend the spectrum of reactions to the vaccine,” the researchers added.

“The patient believed that the vaccine caused her breast growth; however, her concerns were not adequately addressed by her primary care physicians, leading to mistrust in the healthcare system,” the researchers wrote.

The researchers cited others on social media who believe they experienced similar breast growth after the COVID-19 shot, nicknaming it the “Pfizer b**b job.”

NEW: A 19-year-old woman’s breasts stunningly grew from a B cup to a triple G in the six months following her Pfizer COVID-19 vaccination in what researchers are calling a first-of-its-kind case, NY Post reports

— Insider Paper (@TheInsiderPaper) January 7, 2025

From the New York Post:

The study authors pointed to the so-called “Pfizer b**b job” phenomenon — some women claimed their breasts grew after getting the shot, but there’s no evidence that was the case.

The researchers report that while lymph node swelling is a “known side effect” of COVID-19 vaccination, changes to the structure or density of breast tissue are “exceedingly rare.”

The study authors said there’s only been one published case detailing distinctive breast changes after the Pfizer booster, and it was a noticeable lump. This woman did not have a lump.

The woman was found to have a very rare condition in which a benign lesion called PASH causes extreme breast enlargement — fewer than 20 cases have ever been documented.

“This case is the first to demonstrate a temporal association between PASH-associated gigantomastia and a vaccine,” the researchers wrote.

” The patient initially reported tingling paresthesia in her breasts, followed by sudden bilateral growth which worsened after receiving the second (Pfizer mRNA) vaccine dose.
Over 6 months, her breast size increased from a B cup to a triple G” https://t.co/icAofiZd5h pic.twitter.com/465Xd72W86

— They Keep Saying Its Rare (@mRNAdeaths) January 3, 2025

From the Plastic & Reconstructive Surgery-Global Open:

A healthy, nulliparous 19-year-old woman experienced significant breast hypertrophy starting 1 week after receiving the Pfizer COVID-19 vaccine in September 2022. Her medical history was unremarkable, with no hormonal disturbances detected on bloodwork.

The patient initially reported tingling paresthesia in her breasts, followed by sudden bilateral growth which worsened after receiving the second vaccine dose. Over 6 months, her breast size increased from a B cup to a triple G (Fig. 1). Physical examination revealed dense, warm, edematous, ptotic breasts with no palpable masses or axillary lymphadenopathy.

Breast ultrasound and chest computed tomography showed diffuse bilateral breast enlargement with mild axillary lymphadenopathy and hyperattenuating areas likely representing hypertrophic tissue. Core biopsies suggested fibroepithelial lesions, such as fibroadenoma, hamartoma, and PASH. Despite a trial of steroids and antibiotics, symptoms persisted and no clear etiology was identified, leading to the decision of surgical management.

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Eleven months post vaccine, the plastic surgery team opted for bilateral reduction mammoplasty, as breast growth had stabilized for 5 months and comprehensive work-up was normal.

Intraoperatively, a Wise pattern reduction with a superomedial pedicle approach was performed. Despite standard blood loss control methods, there was significant blood loss (1.2–1.5 L), likely due to increased tissue vascularity and inadequate penetration of tumescence in dense tissue. Hemodynamic stability was regained with intravenous fluid support; however, further reduction was limited to minimize greater blood loss. Left and right specimens weighed 1906 and 1664 g, respectively, reducing her breast size from a triple G to a double D (Figs. 2, 3).

Final pathology confirmed hypertrophied glandular breast tissue with multiple well-defined regions of PASH bilaterally (Fig. 3). The patient additionally had increased density of terminal duct lobular units interspersed with PASH.

Due to significant intraoperative blood loss, the patient’s hemoglobin dropped from 11 g/dL preoperatively to 6.7 g/dL postoperatively, necessitating transfusion of 3 units of packed red blood cells over 2 days. By postoperative day 2, her hemoglobin stabilized at 8.1 g/dL, and she was discharged. On postoperative day 3, she returned to the emergency department with fever (103.1°F) and chest pain but remained hemodynamically stable. There was no evidence of infection, transfusion reaction, bleeding, or pulmonary embolism. Her hemoglobin dropped to 7.2 g/dL, and she received 300 mg intravenous Venofer, with plans for further outpatient doses.

At 5 months postoperation, breast asymmetry and areolar hypopigmentation were noted. There has been no recurrence of breast growth, and further breast reduction is being considered to correct asymmetry and return to her normal breast size.

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